Found 147 articles for: "actinic keratosis"
Ingenol Mebutate-Induced Cell Death Patterns in Normal and Cancer Epithelial Cells
October 2012 | Volume 11 | Issue 10 | Original Article | 1181 | Copyright © October 2012
We investigated the proposed necrotic mechanism of ingenol mebutate, a natural compound with anti-cancer properties in human keratinocytes, the human squamous cell carcinoma cell line HSC-5, and HeLa...
Read MoreIngenol Mebutate: Potential for Further Development of Cancer Immunotherapy
October 2012 | Volume 11 | Issue 10 | Original Article | 1156 | Copyright © October 2012
Ingenol mebutate is a diterpene ester derived from the plant Euphorbia peplus and is FDA approved for the topic...
Read MoreDiclofenac Sodium 3% Gel for the Management of Actinic Keratosis: 10+ Years of Cumulative Evidence of Efficacy and Safety
May 2012 | Volume 11 | Issue 5 | Original Article | 600 | Copyright © May 2012
Background: Diclofenac sodium 3% gel (Solaraze®) gained US approval for the treatment of...
Read MoreEvaluation of the Chemopreventative Effects of ALA PDT in Patients With Multiple Actinic Keratoses and a History of Skin Cancer
May 2012 | Volume 11 | Issue 5 | Original Article | 593 | Copyright © May 2012
Background: Actinic keratoses (AKs) are in situ epidermal tumors that may progress to invasive squamous cell carcinomas (SCCs). Aminolevulinic acid with photodynamic therapy (ALA PDT) is a fiel...
Read MoreTreatment of Actinic Keratoses With 5% Topical Imiquimod: A Multicenter Prospective Observational Study from 93 Austrian Office-based Dermatologists
May 2012 | Volume 11 | Issue 5 | Original Article | 574 | Copyright © May 2012
Background: While randomized, controlled trials have generated information about the safety and efficac...
Read MoreSkin Cancer: Prevention and Latest Treatments
May 2012 | Volume 11 | Issue 5 | Editorials | 572 | Copyright © May 2012
PIPELINE PREVIEWS
April 2012 | Volume 11 | Issue 4 | Features | 546 | Copyright © April 2012
Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatologic community. This department may include additional information from th...
Read MoreTop Dermatologic Conditions in Patients of Color: An Analysis of Nationally Representative Data
April 2012 | Volume 11 | Issue 4 | Original Article | 466 | Copyright © April 2012
Background: Some dermatologic disorders are known to be much more common in patients of color, but the leading de...
Read MoreA Comparison of Cryotherapy and Imiquimod for Treatment of Actinic Keratoses: Lesion Clearance, Safety, and Skin Quality Outcomes
December 2011 | Volume 10 | Issue 12 | Original Article | 1432 | Copyright © December 2011
Background: There is limited direct comparative data on imiquimod versus cryotherapy to treat actinic keratoses.<...
Read MoreTreatment of Actinic Cheilitis by Photodynamic Therapy With 5-Aminolevulinic Acid and Blue Light Activation
November 2011 | Volume 10 | Issue 11 | Original Article | 1240 | Copyright © November 2011
Actinic cheilitis (AC), a common disorder of the lower lip, should be treated early to prevent progression to invasive squamous cell carcinoma. This study evaluated the safety and efficacy of photodyn...
Read MoreMetallic Taste as a Side Effect of Topical Fluorouracil Use
October 2011 | Volume 10 | Issue 10 | Case Reports | 1201 | Copyright © October 2011
Topical fluorouracil is widely used for the treatment of precancerous and cancerous lesions of the skin. The most common side effect of this medication is localized irritant dermatitis. The authors re...
Read MoreEffect of Retinoid Pretreatment on Outcomes of Patients Treated by Photodynamic Therapy for Actinic Keratosis of the Hand and Forearm
October 2011 | Volume 10 | Issue 10 | Original Article | 1124 | Copyright © October 2011
Background/Objective: Photodynamic therapy (PDT) with 5-aminolevulinic acid (ALA) has been shown to be useful in ...
Read MoreA Randomized, Blinded, Bilateral Intraindividual, Vehicle-Controlled Trial of the Use of Photodynamic Therapy With 5-Aminolevulinic Acid and Blue Light for the Treatment of Actinic Keratoses of the Upper Extremities
September 2011 | Volume 10 | Issue 9 | Original Article | 1049 | Copyright © September 2011
Background/Objective: Actinic keratoses (AKs) on the upper extremities are difficult to treat. This study compares the ...
Read MorePipeline Previews
June 2011 | Volume 10 | Issue 6 | Features | 683 | Copyright © June 2011
Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatologic community. This d...
Read MoreCLINICAL TRIAL REVIEW
April 2011 | Volume 10 | Issue 4 | Original Article | 426 | Copyright © April 2011
Clinical Trial Review is a JDD department designed to provide physicians with information on drugs and devices undergoing clinical testing. It is our goal to inform the reader of the status of select ...
Read MoreProspective, Case-Based Assessment of Sequential Therapy With Topical Fluorouracil Cream 0.5% and ALA-PDT for the Treatment of Actinic Keratosis
April 2011 | Volume 10 | Issue 4 | Original Article | 372 | Copyright © April 2011
The sequential use of topical therapies and short-incubation photodynamic therapy for actinic keratosis (AK) has not been extensively studied. The ...
Read MoreEruptive Squamous Cell Carcinomas With Keratoacanthoma-like Features in a Patient Treated with Sorafenib
March 2011 | Volume 10 | Issue 3 | Case Reports | 308 | Copyright © March 2011
Sorafenib is a multikinase inhibitor that displays antiproliferative and antiangiogenic properties in the treatment of solid tumors. Commonly administered for the treatment of metastatic or unresectab...
Read MoreComplete Clearance Is Sustained for at Least 12 Months After Treatment of Actinic Keratoses of the Face or Balding Scalp Via Daily Dosing With Imiquimod 3.75% or 2.5% Cream
February 2011 | Volume 10 | Issue 2 | Original Article | 165 | Copyright © February 2011
Objective: Assess long-term, sustained, complete clearance of actinic keratoses after treatment with imiquimod 3.75% or 2.5% cream using two two-week or three-week cycles of daily dosing.
Meth...
Read MoreReview of Actinic Keratosis. Part I:Etiology, Epidemiology and Clinical Presentation
September 2010 | Volume 9 | Issue 9 | Original Article | 1125 | Copyright © September 2010
Clinically, actinic keratoses (solar keratoses) are keratotic lesions that occur on chronically sunlight-exposed skin. Histologically, they are epidermal tumors. Presenting with a spectrum of clinica...
Read MoreNew Histopathological Classification of Actinic Keratosis (Incipient Intraepidermal Squamous Cell Carcinoma)
July 2005 | Volume 4 | Issue 4 | Original Article | 462 | Copyright © July 2005
Actinic keratoses are common, sun-induced lesions that have historically been regarded as “premalignant.” Evidence supports their inclusion along a continuum with squamous cell carcinoma. We prop...
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